This is unpublished

Matthias
Stephan
M.D.
Ph.D.

he, him, his
Physician & Research Faculty
Pinned
Academic
Associate Professor, Clinical Research Division, Fred Hutchinson Cancer Research Center
Associate Professor, Division of Medical Oncology, University of Washington
Adjunct Associate Professor, Bioengineering, UW

Photo: Fred Hutch

Education, Training, Board Certifications 

  • M.D., Medical University of Luebeck, Germany 
  • Ph.D., Cornell University 
  • Postdoctoral training, Massachusetts Institute of Technology 

Expertise  

  • Immunobioengineering 
  • CAR T-cell therapy 
  • Nonviral gene therapy 
  • Nanotechnology 

Affiliations

Publications

Research and/or clinical interests

Dr. Stephan’s laboratory in the Clinical Research Division at Fred Hutchinson Cancer Research Center works at the interface of materials science and immunology, designing synthetic materials that can be used as components of novel cancer immunotherapies. Because certain cells of our immune system can selectively destroy cancerous cells without damaging healthy tissue, engineering approaches grounded in immunology may hold the key to the discovery and development of safe and effective new cancer treatments. To this end, his group takes a materials science–centric engineering approach to create new therapies based in the controlled modulation of the immune system.  

His research efforts are currently focused on  

  • The development of an implantable device to eradicate tumor left behind after surgery. 
  • The design of novel polymeric nanoparticles that can rapidly program tumor-recognizing capabilities into lymphocytes in vivo